TY - GEN
T1 - Modeling study on Calcium-activated Dynamics of Neuronal Dendrites
AU - Katayama, Norihiro
AU - Nakao, Mitsuyuki
AU - Mizutani, Yoshinari
AU - Yamamoto, Mitsuaki
N1 - Publisher Copyright:
©1992 IEEE
PY - 1992
Y1 - 1992
N2 - A mathematical model of active neuronal dendrite is constructed in the discrete form based on physiological informations. The dynandcs of this model is described by calcium-activated regenerative processes with threshold and calcium accumulation system which changes the dynamical properties of the model. Our model is capable of reproducing a stable oscillation in response to a maintained current stimulation. The firing rate in response to the periodic stimulation monotonically increases in a stepwise manner as a function of the amplitude of stimuli. This stimulus-response properties are commonly observed in aM actual neurons and neuron models. The model can also reproduce caldumactivated plateau potential based on bifurcation mechanism parametrized by an intracellular calcium concentration. These dynamical properties coincide with that of actual neuron. Compaitmental dendrite model is constructed by coupling these single compartment models to make up dendritic structure. Active potentials propagating on compaitmental dendrite model mutually interact so that the propagating velocity is modified. Active dendrite which is constructed with the "neuron" could process information throufh its complicated dynamics.
AB - A mathematical model of active neuronal dendrite is constructed in the discrete form based on physiological informations. The dynandcs of this model is described by calcium-activated regenerative processes with threshold and calcium accumulation system which changes the dynamical properties of the model. Our model is capable of reproducing a stable oscillation in response to a maintained current stimulation. The firing rate in response to the periodic stimulation monotonically increases in a stepwise manner as a function of the amplitude of stimuli. This stimulus-response properties are commonly observed in aM actual neurons and neuron models. The model can also reproduce caldumactivated plateau potential based on bifurcation mechanism parametrized by an intracellular calcium concentration. These dynamical properties coincide with that of actual neuron. Compaitmental dendrite model is constructed by coupling these single compartment models to make up dendritic structure. Active potentials propagating on compaitmental dendrite model mutually interact so that the propagating velocity is modified. Active dendrite which is constructed with the "neuron" could process information throufh its complicated dynamics.
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U2 - 10.1109/IJCNN.1992.227121
DO - 10.1109/IJCNN.1992.227121
M3 - Conference contribution
AN - SCOPUS:85132146112
T3 - Proceedings of the International Joint Conference on Neural Networks
SP - 523
EP - 528
BT - Proceedings - 1992 International Joint Conference on Neural Networks, IJCNN 1992
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 1992 International Joint Conference on Neural Networks, IJCNN 1992
Y2 - 7 June 1992 through 11 June 1992
ER -