@article{7c76de8093c040d7885dcd9bd8b538be,
title = "Palladium(0)-catalyzed [4+2] Annulation of Salicylaldehydes and Propargyl Carbonates to Produce 3,4-Dihydro-2-methylene-2H-1-benzopyran-4-ols",
abstract = "Palladium(0)-catalyzed synthesis of 3,4-dihydro-2-methyl-ene-2H-1-benzopyran-4-ols via annulation between salicylaldehyde and propargyl carbonate using a formate reductant is reported herein. The annulation proceeds via common addition of the hydroxyl group in salicylaldehyde to the central carbon of η3-allenyl-/propargylpalladium, wherein the latter is generated through the oxidative addition of propargyl carbonate to the catalyst and subsequent intramolecular umpolung allylation of the aldehyde.",
keywords = "Propargyl carbonate, Salicylaldehyde, [4+2] Umpolung annulation",
author = "Ayumu Kawase and Hirotaka Omura and Takayuki Doi and Hirokazu Tsukamoto",
note = "Funding Information: This work was partly supported by The Research Foundation for Pharmaceutical Sciences, SUNTORY FOUNDATION for LIFE SCIENCES, Platform Project for Supporting Drug Discovery and Life Science Research (Basis for Supporting Innovative Drug Discovery and Life Science Research (BINDS)) from AMED under Grant Number JP18am0101095 and JP18am0101100, and JSPS KAKENHI Grant Numbers JP24590004 and JP15H05837 in Middle Molecular Strategy. We thank Dr. Saori Tanii for her help with obtaining X-ray crystal structures. The authors would like to thank Enago (www.enago.jp) for the English language review. Publisher Copyright: {\textcopyright} 2019 The Chemical Society of Japan",
year = "2019",
doi = "10.1246/cl.190642",
language = "English",
volume = "48",
pages = "1402--1405",
journal = "Chemistry Letters",
issn = "0366-7022",
publisher = "Chemical Society of Japan",
number = "11",
}