TY - JOUR
T1 - Positive expression of the immunoglobulin superfamily protein IZUMO on human sperm of severely infertile male patients
AU - Hayasaka, Shinichi
AU - Terada, Yukihiro
AU - Inoue, Naokazu
AU - Okabe, Masaru
AU - Yaegashi, Nobuo
AU - Okamura, Kunihiro
PY - 2007/7
Y1 - 2007/7
N2 - Recently, the immunoglobulin superfamily protein IZUMO on the sperm surface was identified as being essential for sperm-egg fusion. Although we examined the expression of IZUMO on sperm of 13 male infertile patients with severe oligozoospermia and/or athenozoospermia and 12 infertile patients with fertilization failure in previous conventional IVF to determine whether it is varied in infertility patients, we could not identify any patients with IZUMO negative by immunocytochemistry.
AB - Recently, the immunoglobulin superfamily protein IZUMO on the sperm surface was identified as being essential for sperm-egg fusion. Although we examined the expression of IZUMO on sperm of 13 male infertile patients with severe oligozoospermia and/or athenozoospermia and 12 infertile patients with fertilization failure in previous conventional IVF to determine whether it is varied in infertility patients, we could not identify any patients with IZUMO negative by immunocytochemistry.
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UR - http://www.scopus.com/inward/citedby.url?scp=34347252299&partnerID=8YFLogxK
U2 - 10.1016/j.fertnstert.2006.11.086
DO - 10.1016/j.fertnstert.2006.11.086
M3 - Article
C2 - 17296188
AN - SCOPUS:34347252299
SN - 0015-0282
VL - 88
SP - 214
EP - 216
JO - Fertility and Sterility
JF - Fertility and Sterility
IS - 1
ER -