TY - GEN
T1 - Simulation study on hierarchical information processing on the active neuronal dendrites
AU - Katayama, Norihiro
AU - Nakao, Mitsuyuki
AU - Mizutani, Yoshinari
AU - Yamamoto, Mitsuaki
PY - 1993
Y1 - 1993
N2 - Dynamics of a pyramidal neuron in hippocampus (CA3 neuron) is modeled in a discrete form based on physiological findings, which is known to involve dendritic calcium-activated dynamics. Responses of the CA3 neuron model to excitatory stimulus on the apical dendrites is studied under the varied somatic inhibition. Computer simulations show the following phenomena: The CA3 neuron model behaves in the spatially cooperative manner under the weak somatic inhibition. On the other hand, when the somatic inhibition is strong, dendritic activities are forced to be localized. These results suggest that proximal dendrite branches could control the dendritic interaction among more distal ones. Highly organized neuronal information processing might be possible by the cooperation of the hierarchically interacting dendrite system and the distribution pattern of synapses on it.
AB - Dynamics of a pyramidal neuron in hippocampus (CA3 neuron) is modeled in a discrete form based on physiological findings, which is known to involve dendritic calcium-activated dynamics. Responses of the CA3 neuron model to excitatory stimulus on the apical dendrites is studied under the varied somatic inhibition. Computer simulations show the following phenomena: The CA3 neuron model behaves in the spatially cooperative manner under the weak somatic inhibition. On the other hand, when the somatic inhibition is strong, dendritic activities are forced to be localized. These results suggest that proximal dendrite branches could control the dendritic interaction among more distal ones. Highly organized neuronal information processing might be possible by the cooperation of the hierarchically interacting dendrite system and the distribution pattern of synapses on it.
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M3 - Conference contribution
AN - SCOPUS:0027848467
SN - 0780314212
SN - 9780780314214
T3 - Proceedings of the International Joint Conference on Neural Networks
SP - 123
EP - 126
BT - Proceedings of the International Joint Conference on Neural Networks
PB - Publ by IEEE
T2 - Proceedings of 1993 International Joint Conference on Neural Networks. Part 1 (of 3)
Y2 - 25 October 1993 through 29 October 1993
ER -