@article{d2420d298d5e4fff89dee65c01f3a4c6,
title = "Solution structure of the Eps15 homology domain of a human POB1 (partner of RalBP1)",
abstract = "The solution structure of the Eps15 homology (EH) domain of a human POB1 (partner of RalBP1) has been determined by uniform 13C/15N labeling and heteronuclear multidimensional nuclear magnetic resonance spectroscopy. The POB1 EH domain consists of two EF-hand structures, and the second one binds a calcium ion. In the calcium-bound state, the orientation of the fourth α-helix relative to the other helices of the POB1 EH domain is slightly different from that of calbindin, and much more different from those of calmodulin and troponin C, on the basis of their atomic coordinates. Copyright (C) 1999 Federation of European Biochemical Societies.",
keywords = "Calcium-binding protein, EH domain, Nuclear magnetic resonance, POB1, Solution structure",
author = "Seizo Koshiba and Takanori Kigawa and Junji Iwahara and Akira Kikuchi and Shigeyuki Yokoyama",
note = "Funding Information: We thank Drs. K. Takio and N. Domae for performing the mass spectrometry. We also thank Dr. M. Shirouzu for many helpful discussions. This work was supported by Grants-in-Aid from the Ministry of Education, Science, Sports and Culture, Japan.",
year = "1999",
month = jan,
day = "15",
doi = "10.1016/S0014-5793(98)01644-5",
language = "English",
volume = "442",
pages = "138--142",
journal = "FEBS Letters",
issn = "0014-5793",
publisher = "Wiley-Blackwell",
number = "2-3",
}