抄録
We developed a novel artificial chaperone and drug delivery system using cholesteryl group-bearing pullulan (CHP) nanogels. In this report, we synthesized cholesteryl group-bearing cluster dextrin which is highly branched dextrin with narrow molecular weight distribution (CH-CDex). The number of cholesteryl groups per 100 glucose units were 1.5(CH-CDex1.5) and 2.4(CH-CDex2.4) determined by 1H-NMR. Solution properties of CH-CDex in water were investigated by DLS and MALS. CH-CDex formed self-associates consisting of 2-3(CH-CDex1.5) and 3-4(CH-CDex2.4) CH-CDex macromolecules, and the particle size (diameter) was 29.4 nm(CH-CDex1.5) and 24.6nm(CH-CDex2.4) by DLS.
本文言語 | English |
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ページ | 2022 |
ページ数 | 1 |
出版ステータス | Published - 2006 |
外部発表 | はい |
イベント | 55th SPSJ Annual Meeting - Nagoya, Japan 継続期間: 2006 5月 24 → 2006 5月 26 |
Other
Other | 55th SPSJ Annual Meeting |
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国/地域 | Japan |
City | Nagoya |
Period | 06/5/24 → 06/5/26 |
ASJC Scopus subject areas
- 工学(全般)