Studies on in vitro activity of t-1220 and clinical experience in the treatment of respiratory infections

Akira Watanabe; Masako Sasaki; Yukinor Yonemoto; Sonok Saito

doi:10.11250/chemotherapy1953.25.967

Studies on in vitro activity of t-1220 and clinical experience in the treatment of respiratory infections

Akira Watanabe, Masako Sasaki, Yukinor Yonemoto, Sonok Saito

研究成果: Article › 査読

抄録

Antimicrobial activity of T-1220, a new penicillin derivative, was studied. The drug showed lower levels of MICs than those of Sulbenicillin against clinical isolates of Klebsiella pneumoniae and Pseudomonas aeruginosa. Clinical evaluation of the drug was made by intravenous administration to a total 7 cases with secondary respiratory tract infections with gram negative bacilli. In 2 cases the drug was withdrawn because of the onset of chill and fever during the drip infusion in a case and of eruption in the other.

本文言語	English
ページ（範囲）	967-972
ページ数	6
ジャーナル	Chemotherapy
巻	25
号	5
DOI	https://doi.org/10.11250/chemotherapy1953.25.967
出版ステータス	Published - 1977 1月 1

ASJC Scopus subject areas

薬理学（医学）
感染症
薬理学
創薬
腫瘍学

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

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10.11250/chemotherapy1953.25.967

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Studies on in vitro activity of t-1220 and clinical experience in the treatment of respiratory infections

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ASJC Scopus subject areas

UN SDG

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