Synthesis and Resolution of a Chiral Open-Chain Host Having a Partial Structure of p-tert-Butylsulfinylcalix[4]arene

Atsuya Sakamoto, Gekko Patria Budiutama, Yoshihiro Takayama, Naoya Morohashi, Tetsutaro Hattori

研究成果: Article査読

1 被引用数 (Scopus)

抄録

An open-chain carboxylic acid host with a chiral sulfinyl group (4) was synthesized from 3,3¤-thiobis[(5-tert-butyl-2-hydroxyphenyl)acetic acid] (2) by oxidation of the epithio linkage with mCPBA, followed by acid-catalyzed monoesterification with propan-1-ol. The monoester was resolved via diastereomeric salt formation using quinidine as a resolving agent. The absolute configuration of (+)-4 was assigned to be (R) by X-ray analysis.

本文言語English
ページ(範囲)440-442
ページ数3
ジャーナルBulletin of the Chemical Society of Japan
95
3
DOI
出版ステータスPublished - 2022

ASJC Scopus subject areas

  • 化学 (全般)

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