Synthesis of Highly Substituted Pyridines through Copper-Catalyzed Condensation of Oximes and α,β-Unsaturated Imines

Wei Wen Tan, Yew Jin Ong, Naohiko Yoshikai

研究成果: Article査読

113 被引用数 (Scopus)

抄録

A copper-catalyzed condensation reaction of oxime acetates and α,β-unsaturated ketimines to give pyridine derivatives is reported. The reaction features mild conditions, high functional-group compatibility, and high regioselectivity with respect to unsymmetrical oxime acetates, thus allowing the preparation of a wide range of polysubstituted pyridines, many of which are not readily accessible by conventional condensation methods.

本文言語English
ページ(範囲)8240-8244
ページ数5
ジャーナルAngewandte Chemie - International Edition
56
28
DOI
出版ステータスPublished - 2017 7月 3
外部発表はい

ASJC Scopus subject areas

  • 触媒
  • 化学 (全般)

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