The analysis of surgical lung biopsy and explanted lung specimens sheds light on the pathological progression of chronic bird-related hypersensitivity pneumonitis

Satoshi Hanzawa, Tomoya Tateishi, Tamiko Takemura, Yoshinori Okada, Yoshihito Yamada, Masafumi Noda, Yasunari Miyazaki, Naohiko Inase

研究成果: ジャーナルへの寄稿学術論文査読

5 被引用数 (Scopus)

抄録

Chronic hypersensitivity pneumonitis is an interstitial pneumonia caused by an immunological reaction to the chronic inhalation of an antigen. Little is known, however, about the pathological change of the pulmonary lesions. A 33-year-old man was diagnosed with chronic bird-related hypersensitivity pneumonitis based on the findings of a surgical lung biopsy and an inhalation provocation test. He underwent lung transplantation at 8 years after the diagnosis because of disease progression. We conclude that the analysis of the explant suggests that the presence of extensive fibrosis in the centrilobular and perilobular area with bridging fibrosis is a form of pathological progression of chronic hypersensitivity pneumonitis.

本文言語英語
ページ(範囲)1145-1150
ページ数6
ジャーナルInternal Medicine
58
8
DOI
出版ステータス出版済み - 2019

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