抄録
Total synthesis of 13-demethyllyngbyaloside B, an unnatural analogue of a marine macrolide glycoside lyngbyaloside B, has been achieved. The 14-membered macrocyclic backbone was constructed in a convergent manner via esterification and ring-closing metathesis. The bromodiene side chain was introduced by means of a Stille-type reaction and a subsequent bromodesilylation. Finally, the rhamnopyranose unit was stereoselectively introduced by glycosylation under Schmidt conditions.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 1630-1633 |
| ページ数 | 4 |
| ジャーナル | Organic letters |
| 巻 | 15 |
| 号 | 7 |
| DOI | |
| 出版ステータス | Published - 2013 4月 5 |
ASJC Scopus subject areas
- 生化学
- 物理化学および理論化学
- 有機化学
UN SDG
この成果は、次の持続可能な開発目標に貢献しています
