@article{2a14156117794aa8a2408d0911cbe957,
title = "Toward the Total Synthesis of Amphidinolide N: Synthesis of the C8-C29 Fragment",
abstract = "A synthesis of the C8-C29 fragment of amphidinolide N, a potent cytotoxic macrolide isolated from the marine dinoflagellate Amphidinium sp., has been achieved. The key features of the synthesis involve a convergent union of the C9-C15 and C16-C29 fragments by Steglich esterification and the construction of a pyran unit through a Tebbe methylenation/ring-closing metathesis sequence.",
author = "Yuki Kawashima and Atsushi Toyoshima and Haruhiko Fuwa and Makoto Sasaki",
note = "Funding Information: We thank Kaneka Corporation for donating (S)-Roche ester. This work was financially supported in part by a Grants-in-Aid for Scientific Research (B) (25282228) and Scientific Research on Innovative Areas {"}Chemical Biology of Natural Products{"} (23102016)37 from the Japan Society for the Promotion of Science (JSPS).",
year = "2016",
month = may,
day = "6",
doi = "10.1021/acs.orglett.6b00871",
language = "English",
volume = "18",
pages = "2232--2235",
journal = "Organic Letters",
issn = "1523-7060",
publisher = "American Chemical Society",
number = "9",
}
