Transition-Metal-Free Intermolecular Hydrocarbonation of Styrenes Mediated by NaH/1,10-Phenanthroline

Kanako Nozawa-Kumada, So Onuma, Kanako Ono, Tomohiro Kumagai, Yuki Iwakawa, Katsuhiko Sato, Masanori Shigeno, Yoshinori Kondo

研究成果: Article査読


A transition-metal-free intermolecular coupling reaction of halocompounds with styrenes in the presence of NaH and 1,10-phenanthroline was developed. This reaction afforded hydrocarbonated products with complete anti-Markovnikov selectivity. The method allows the use of a wide range of halocompounds, including aryl and alkyl halides, and good functional group tolerance. Detailed mechanistic studies indicated that an anilide anion generated in situ by the NaH-mediated reduction of 1,10-phenanthroline works as an electron donor and a hydrogen source.

ジャーナルChemistry - A European Journal
出版ステータスAccepted/In press - 2023

ASJC Scopus subject areas

  • 触媒
  • 有機化学


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