Two Cases of Locally Recurrent Rectal Cancer Successfully Treated by Carbon Ion Radiotherapy

Keigo Kanehara, Shinobu Ohnuma, Hideyuki Suzuki, Akihiro Yamamura, Hideaki Karasawa, Atsushi Kohyama, Takeshi Aoki, Kazuhiro Watanabe, Naoki Tanaka, Hiroaki Musha, Fuyuhiko Motoi, Takashi Kamei, Takeshi Naitoh, Michiaki Unno

研究成果: ジャーナルへの寄稿学術論文査読

抄録

Case 1: A female patient in her 60s underwent laparoscopic intersphincteric resection for rectal cancer. After 42 months, the serum level of carcinoembryonic antigen(CEA)was elevated, and PET-CT showed a locally recurrent rectal cancer that increased FDG-uptake. Carbon ion radiotherapy(CIRT)(73.6 GyE/16 Fr)was performed. Serum CEA level and FDG-uptake were normalized. No regrowth of tumor has been found for 12 months. Case 2: A female patient in her 60s underwent abdominoperineal resection for rectal cancer. After 42 months, the serum level of CEA was elevated, and CT revealed a local recurrence of rectal cancer. Subsequently, the tumor was resected; however, resection margin was microscopically positive. Therefore, chemoradiotherapy(S-1, 60 Gy)was performed. At 31 months after local resection, a re-recurrent tumor was noted in her left ischium. Therefore, CIRT(70.4 GyE/16 Fr)was performed. Serum CEA level and FDG-uptake were normalized. No regrowth of tumor has been found for 24 months. CIRT is an effective therapy for locally recurrent rectal cancer.

本文言語英語
ページ(範囲)1940-1942
ページ数3
ジャーナルJapanese Journal of Cancer and Chemotherapy
45
13
出版ステータス出版済み - 2018 12月 1

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